No prior knowledge required — just common sense and a brain

As a 16 year old new to machine learning, I came across a ton of acronyms which had absolutely no meaning: PCA, SVD, MLP, etc. It’s almost like FDR’s alphabet soup from WWII (CCC, WPA, PWA (for all you history buffs ;)). …

Stalling The More Permanent Future Pandemic We Still Can Prevent

You’re a tourist visiting India for the first time. You’ve had a great time so far, chatting with the locals and building a great relationship, trying new food, and visiting landmark tourist destinations that’ve been on your bucket list for quite some time. You get back to your cottage in…

Ok. So 2020 wasn’t what we all expected it to be….

Many of my new year's resolutions/goals from last year involved traveling to different countries to spend time in nature and attending my favorite conferences in person. I couldn’t make those happen, but I’m still happy with the way that…

2020 has objectively been a hard time for science, with the rearrangement of project priorities and funding and the lack of serendipitous in-person conversations at conferences. We won’t have pictures like those taken at the Solvay conference, scientists shoulder to shoulder. …

An attempt at answering humanity’s (arguably) most important question through the lens of a 17th-century philosopher

An Introduction to the Classic Descartes Story

What if everything that you’re seeing in front of you is completely false? Sounds absurd, but the truth is, there’s no way to deny it. You could be dreaming, or maybe we’re in some sort of simulation where we’re being programmed to think in certain ways. Again — these thoughts…

On Eternal Recurrence, Dimorphism, and Superhumans

When you think about people in history who went against the rest of society to conceive of an ultimate truth, what often comes to mind? …

Why is it that we still haven’t been able to figure out how to cure diseases like Alzheimer’s? It’s mainly because:

  1. We don’t understand the main mechanism of the disease (the pathways involved in misfolded amyloid accumulation). …

Stealing the most rewards 👀🏆 using reinforcement learning

In this article, I go over the basics of reinforcement learning and the BANDIT algorithm along with explained code implementations. Skip the first section if you’d like to jump to the code implementations.

Background

Imagine that you’re playing games at a casino and you have multiple slot machines that you can…

Get an Intuition for the Difference between SGD vs RMSprop vs Adam optimizers

Smooth loss landscape visualization. Credit — https://www.cs.umd.edu/~tomg/projects/landscapes/

When people first start out machine learning in PyTorch, you might see a PyTorch script like this.

Let’s decipher the black box — A Simple Explanation to Force Field functions like CHARMM, programs like Rosetta, and cutting-edge Deep Learning Algorithms

If you thought about each of our cells like a miniature city, our proteins would play every role from transportation to housing, from banking to agriculture. They have complex three-dimensional structures and they do pretty much everything in our cells. I’d argue that our proteins should receive more attention than…

Mukundh Murthy

Innovator passionate about the intersection between structural biology, machine learning, and chemiinformatics. Currently @ 99andbeyond.

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